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Postal Explorer > Publication 52 - Hazardous, Restricted, and Perishable Mail > Appendix C USPS Packaging Instructions for Mailable Hazardous Materials > USPS Packaging Instruction 6G
Forensic material in Risk Group 1 sent on behalf of a U.S. government, state,
local, or Indian tribal government agency must be packaged under Packaging
Instruction 6G. Forensic material known or suspected to contain a Risk
Group 4 infectious substance must be packaged under Packaging Instruction
6B. Forensic material known or suspected to contain a Risk Group 2 or 3
pathogen is mailable as First-Class Mail, Priority Mail, or Express Mail when
packaged as discribed below:
• Not applicable
• International Mail: Only via registered airmail letter-post as permitted in
622.2 and IMM 135 when written approval has been granted by the
Manager, Mailing Standards prior to mailing.
• Domestic Mail: Forensic material known or suspected to contain a
Risk Group 2 or 3 pathogen is mailable as First-Class Mail, Priority
Mail, or Express Mail.
Primary Receptacle
• Forensic material must be packaged in a securely sealed primary
receptacle.
• The primary receptacle must be surrounded by sufficient absorbent
material (for liquids) and cushioning material to protect the primary
container from breakage.
• The absorbent material must be capable of taking up the entire liquid
contents of the primary receptacle in case of leakage.
• The primary receptacle must be marked with the international
biohazard symbol (see Exhibit 346.32e).

Secondary Container
• The primary receptacle and the absorbent and cushioning material
must be enclosed in a watertight and securely sealed secondary
container.
• The secondary container must also display the international biohazard
symbol (see Exhibit 346.42c).
Outer Shipping Container
• The secondary container must fit sungly packed within a strong outer
shipping container that is securely sealed.
Marking/Documentation
• A shipping paper and content markings on the outer shipping container
are not required.
• Each mailpiece must have a complete delivery and return address.
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